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Compounding Vessel
Created with Pixso. 1000L GMP Pharmaceutical Dilution & Concentration Vessel AISI316L Electro-Polished Jacketed Tank with Spun Conical Head and Magnetic Agitator

1000L GMP Pharmaceutical Dilution & Concentration Vessel AISI316L Electro-Polished Jacketed Tank with Spun Conical Head and Magnetic Agitator

Brand Name: LINGYAO
Model Number: LYPYG-1000
MOQ: 1
Price: 5000-50000uSD/unit
Delivery Time: 30-90 days
Payment Terms: L/C,D/A,D/P,T/T
Detail Information
Place of Origin:
China
Certification:
CE
Name:
Compounding Vessel
Working Volumi:
1000L
Stirrer Type:
Magnetic Stirrer
Material:
316L For Liquid Contact
Jacket:
Dual-duty
CIP:
Available
SIP:
Available
Valves:
Pharmaceutical
PLC:
Complies With FDA 21 CFR Part 11
HML:
Complies With FDA 21 CFR Part 11
Packaging Details:
carton,wood,carton,pallets
Supply Ability:
5-20 units per month
Product Description

      1000L GMP Pharmaceutical Dilution & Concentration Vessel AISI316L Electro-Polished Jacketed Tank with Spun Conical Head and Magnetic Agitator

Product Features
      Built around a 1000 L working capacity, this sanitary-grade vessel serves as the dilution and concentration stage of a liquid preparation line. The shell-and-head assembly is cold-spun into a conical profile without welded seams in the product zone, while the interior is electrolytically mirror-polished to a sanitary finish that resists residue build-up. A full-jacketed wall allows both steam-assisted warming and chilled-medium cooling on the same unit, so a single tank can cover heat-driven dissolution and cold holding without changeover. The bottom-entry magnetic drive keeps the product path seal-free during agitation, and every wetted surface is drainable to a low-point outlet for reliable drainage and cleaning.

Technical Parameters
Parameter Specification
Nominal / Working Volume 1000 L (jacketed sanitary vessel)
Product-Contact Material AISI 316L stainless steel
Non-Contact / Support Parts AISI 304 stainless steel
Internal Finish Electrolytic mirror polishing, sanitary grade, Ra ≤ 0.4 μm
External Finish Satin / brushed or mirror, customer's choice
Head Configuration Conical head, cold-spun forming, seam-free in product zone
Jacket Type Full sandwich (double) jacket for heating and cooling
Heating Medium Low-pressure steam or hot water
Cooling Medium Chilled water / glycol solution
Agitator Bottom-mounted magnetic drive, seal-free, inverter speed control
Spray Device Rotating or fixed CIP spray balls, 360° coverage
Drainage Low-point diaphragm valve, self-draining design
Instrumentation PT100 temperature probe, pressure gauge, level indication
Manhole / Access Sanitary manhole with sight glass and spray inlet
Support Adjustable sanitary legs with load-cell mounting provision
Standards Designed and fabricated to GMP requirements
Usage Scenarios
Widely applied in injection and large-volume parenteral (LVP/SVP) lines, oral liquid and syrup plants, ophthalmic solution workshops, and API reconstitution areas where a bulk solution must be diluted to target strength, concentrated by controlled heating, or held at a defined temperature before filtration and filling. The dual-purpose jacket makes it equally suitable for processes that alternate between warm dissolution and cold intermediate storage, and the drainable conical bottom supports validated cleaning between batches or products.
Key Applications
  • Controlled Dilution: Metered addition of diluent with agitation to reach the required assay or concentration uniformly.
  • Concentration & Dissolution: Jacket-assisted heating to accelerate solute dissolution or gently reduce solvent volume under controlled temperature.
  • Intermediate Holding: Temperature-stable buffer storage between the preparation stage and downstream sterile filtration or filling.
  • Buffer & Wash Solution Preparation: Preparation of cleaning, rinsing and buffer liquids for upstream and downstream equipment.
Frequently Asked Questions (FAQs)
  • Q: Can the same tank both heat and cool?
    A: Yes. The sandwich jacket accepts low-pressure steam or hot water for heating and chilled water/glycol for cooling; the medium is switched at the utility manifold, so no second vessel is required.
  • Q: Is the interior suitable for direct product contact and cleaning?
    A: The wetted surface is AISI 316L with electrolytic mirror polishing and a self-draining conical profile, combined with 360° spray balls, which supports effective CIP and minimizes residue retention.
  • Q: How is leakage risk at the agitator avoided?
    A: Agitation is transmitted by a magnetic coupling through the tank wall, so there is no rotating shaft seal inside the product zone — a common source of contamination and maintenance downtime.
  • Q: Can it be integrated into an existing liquid preparation line?
    A: Yes. Inlet, outlet, spray, vent and instrument connections are arranged to customer P&ID, and the vessel can be linked with CIP skids, filtration units and filling machines on the same skid.
Regulatory Compliance & Validation Support
Fabrication follows GMP-oriented sanitary design: no dead legs in the product path, fully drainable geometry, polished and passivated wetted surfaces, and hygienic connections throughout. Documentation supplied with each unit includes material certificates for product-contact stainless steel, surface finish and passivation records, welding and pressure test reports, dimensional drawings, and operation and maintenance manuals. On request we can support FAT/SAT execution and provide the base documents normally referenced in IQ/OQ preparation, helping your quality team shorten the qualification cycle before commissioning.